In 1968, in a remote part of Canada, a mysterious child is born: a baby who appears to be neither fully boy nor girl, but both at once. Only three people share the secret - the baby's parents and a trusted neighbour. Together the adults make a difficult decision: to go through surgery and raise the child as a boy named Wayne.
But as Wayne grows up within the hyper-male hunting culture of his father, his shadow-self - a girl he thinks of as 'Annabel' - is never entirely extinguished, and indeed is secretly nurtured by the women in his life. As Wayne approaches adulthood, and its emotional and physical demands, the woman inside him begins to cry out. The changes that follow are momentous not just for him, but for the three adults that have guarded his secret.