As a teenager, Lucy McBride, is woken by the sound of classical music, and from that moment she devotes herself to the study of the cello. Her fascination later leads her to Venice, and to Fortuny, the master cellist. They begin an intense, ill-fated affair, but as emotions and desires tangle with hopes and dreams, they must struggle to decide how their symphony must end.
Rome, AD 34: Vespasian is serving as a military officer on the outskirts of the Empire. But political events in Rome - Tiberius's increasing debauchery, the escalating grain crisis - draw him back to the city. When Caligula becomes Emperor, Vespasian believes that things will improve. Instead, the young emperor deteriorates from Rome's shining star to a blood-crazed, incestuous, all-powerful madman.